Document Type

Article

Publication Date

3-1-2004

Keywords

Bacteria, Electrical stimulation, Wound healing

Abstract

We evaluated the efficacy of common electrical stimulation (ES) types on bacterial growth in vitro using clinically relevant conditions. Four types of ES-continuous micro-amperage direct current (μADC), high-voltage pulsed current (HVPC), low-voltage monophasic milliamperage pulsed current (LVMmAPC), and low-voltage biphasic milliamperage pulsed current (LVBmAPC)-were each applied to a separate set of culture plates containing Staphylococcus aureus for 1 h at 37°C on 3 consecutive days. After ES treatment, the zone of inhibition surrounding each electrode was measured. Zone of inhibition measurements showed a significant inhibitory effect for continuous μADC and HVPC (p < 0.05), but not for LVM-mAPC and LVBmAPC. Differences in bacterial growth inhibition were not found for polarity and time. These data suggest that for infected wounds, HVPC and continuous μADC treatments may have an initial bacterial inhibitory effect, which does not significantly change with subsequent treatments.

Journal Title

Journal of Rehabilitation Research and Development

Volume

41

Issue

2

First Page

139

Last Page

146

DOI

https://doi.org/10.1682/JRRD.2004.02.0139

First Department

Rehabilitation Services

Acknowledgements

Free article retrieved March 25, 2021 from https://www.rehab.research.va.gov/jour/04/41/2/pdf/Merriman.pdf

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