Traditional Kava Beverage Consumption and Liver Function Tests in a Predominantly Tongan Population in Hawaii

Document Type

Article

Publication Date

7-1-2007

Keywords

Beverage, Hepatotoxicity, Kava, Liver function test, Pacific Islanders

Abstract

Purpose. To determine the effects of traditionally prepared kava beverages on the liver function tests of regular kava beverage consumers in a population of Tongan and non-Tongan residents of Hawaii (Oahu). Methods. The liver function tests of 31 healthy adult kava drinkers were compared against a control group of 31 healthy adult non-kava drinkers. Subjects were recruited from the general population, a kava bar, and Tongan kava drinking circles. The liver function profile included AST, ALT, ALP, GGT, and bilirubin (total and direct). Other tests included total protein, albumin, and screens for viral hepatitis and hemochromatosis when indicated. Results. Chronic kava beverage consumption was associated with elevation of GGT in 65% of the kava drinkers versus 26% in the controls (P =.005). ALP was elevated in 23% of kava drinkers versus 3% in the controls (P =.053). Conclusion. Heavy kava beverage consumption was associated with significantly elevated GGT levels. Copyright © Informa Healthcare.

Journal Title

Clinical Toxicology

Volume

45

Issue

5

First Page

549

Last Page

556

DOI

10.1080/15563650701365875

First Department

Population Health, Nutrition & Wellness

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