Presenter Information

Seth Stacey, Andrews University

Abstract

The goal of this project is to investigate the use of NIR-spectroscopy to quantify the number of OH functional groups attached to poly (amido amine) or PAMAM dendrimers in a manner that is quick, cost effective and easily reproducible. Obtaining the approximate number of hydroxyl functional groups (OH#) in a dendrimer is crucial in determining what role it can play in bonding and reactivity to other molecules. NIR-spectroscopy has the potential to allow for the recovery of the sample or at least to minimize the amount needed for analysis while providing an accurate determination of the OH# of a dendrimer.

Acknowledgments

J.N. Andrews Honors Scholar and Undergraduate Research Scholar

Advisor: Ryan Hayes, Chemistry & Biochemistry

Location

Buller Hallway

Start Date

3-6-2015 2:30 PM

End Date

3-6-2015 4:00 PM

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Included in

Chemistry Commons

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Mar 6th, 2:30 PM Mar 6th, 4:00 PM

P-22 Hydroxyl Functional Group Number Determination of PAMAM Dendrimers with NIR-spectroscopy

Buller Hallway

The goal of this project is to investigate the use of NIR-spectroscopy to quantify the number of OH functional groups attached to poly (amido amine) or PAMAM dendrimers in a manner that is quick, cost effective and easily reproducible. Obtaining the approximate number of hydroxyl functional groups (OH#) in a dendrimer is crucial in determining what role it can play in bonding and reactivity to other molecules. NIR-spectroscopy has the potential to allow for the recovery of the sample or at least to minimize the amount needed for analysis while providing an accurate determination of the OH# of a dendrimer.