Abstract
The goal of this project is to investigate the use of NIR-spectroscopy to quantify the number of OH functional groups attached to poly (amido amine) or PAMAM dendrimers in a manner that is quick, cost effective and easily reproducible. Obtaining the approximate number of hydroxyl functional groups (OH#) in a dendrimer is crucial in determining what role it can play in bonding and reactivity to other molecules. NIR-spectroscopy has the potential to allow for the recovery of the sample or at least to minimize the amount needed for analysis while providing an accurate determination of the OH# of a dendrimer.
Thesis Record URL
Location
Buller Hallway
Start Date
3-6-2015 2:30 PM
End Date
3-6-2015 4:00 PM
P-22 Hydroxyl Functional Group Number Determination of PAMAM Dendrimers with NIR-spectroscopy
Buller Hallway
The goal of this project is to investigate the use of NIR-spectroscopy to quantify the number of OH functional groups attached to poly (amido amine) or PAMAM dendrimers in a manner that is quick, cost effective and easily reproducible. Obtaining the approximate number of hydroxyl functional groups (OH#) in a dendrimer is crucial in determining what role it can play in bonding and reactivity to other molecules. NIR-spectroscopy has the potential to allow for the recovery of the sample or at least to minimize the amount needed for analysis while providing an accurate determination of the OH# of a dendrimer.
Acknowledgments
J.N. Andrews Honors Scholar and Undergraduate Research Scholar
Advisor: Ryan Hayes, Chemistry & Biochemistry