Abstract
My research project is focused around a specific gene—cytosolic carboxypeptidase 5 (CCP5). Previous research suggests that the CCP5 gene is essential for the modification of α-tubulin which is necessary for normal growth of cilia in the olfactory pit of zebrafish. It is my goal to confirm the role of the CCP5 gene in olfactory ciliary growth using scanning electron microscopy. Using a CCP5-MO to knockdown, the gene I can compare the resulting phenotype to that of a control specimen in order to determine any visible differences with respect to cilia morphology.
Thesis Record URL
Location
Buller Hallway
Start Date
3-7-2014 2:30 PM
End Date
3-7-2014 4:00 PM
P-11 Cytosolic Carboxypeptidase 5 (CCP5) and Cilia Development in Zebrafish
Buller Hallway
My research project is focused around a specific gene—cytosolic carboxypeptidase 5 (CCP5). Previous research suggests that the CCP5 gene is essential for the modification of α-tubulin which is necessary for normal growth of cilia in the olfactory pit of zebrafish. It is my goal to confirm the role of the CCP5 gene in olfactory ciliary growth using scanning electron microscopy. Using a CCP5-MO to knockdown, the gene I can compare the resulting phenotype to that of a control specimen in order to determine any visible differences with respect to cilia morphology.
Acknowledgments
J.N. Andrews Honors Scholar
Advisor: Peter Lyons, Biology