Date of Award
7-7-2025
Document Type
Capstone Project
Degree Name
Master of Science in Medical Laboratory Sciences (MSMLS)
Department
Department of Medical Laboratory Sciences
Abstract
Abstract
This capstone project aims to enhance diagnostic reliability in a clinical laboratory by validating centrifuge performance and implementing an adult education-based training program within a quality management framework. Twenty archived, de-identified whole blood samples were analyzed to compare the performance of a new centrifuge with an existing model, focusing on plasma volume, hemolysis index, and Tacrolimus concentration.
The study demonstrated statistical and clinical equivalence between the devices, supporting the implementation of the new centrifuge. A staff training program, grounded in andragogical principles and guided by transformational leadership and Kotter’s 8-Step Change Model, was developed to integrate validation practices into routine laboratory practice. Outcomes included improved sample integrity, enhanced documentation practices, and increased inspection readiness.
The project offers a scalable model for linking technical rigor, adult education, and quality leadership to promote continuous improvement and regulatory compliance in clinical laboratories.
Recommended Citation
Agoki, Chris, "Enhancing Diagnostic Reliability through Centrifuge Validation and Staff Education: Quality Management Initiative in a Clinical Laboratory" (2025). MSMLS Capstone Projects. 1.
https://digitalcommons.andrews.edu/msmls/1