The Effect of a Novel Hybrid Drug on the Inositol Signaling System in the Yeast Saccharomyces Cerevisiae

Hailey Kim, Andrews UniversityFollow

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Department

Chemistry and Biochemistry

Abstract

Bipolar Disorder is one of the major mental illnesses in the world. While there is insufficient understanding of the mechanism of the disease, many of the drugs used for treatment appear to work via the inositol signaling system. The purpose of this study is to develop a novel hybrid drug-containing valproate and caffeine and determine its impact on the inositol cell signaling system. To do so, the yeast Saccharomyces cerevisiae was grown in varying concentrations of the hybrid drug, and inositol concentration will be measured in cell extracts.

Acknowledgments

Advisors: Desmond Murray & Marlene Murray

Session

Department of Chemistry & Biochemistry

Event Website

https://www.andrews.edu/services/research/research_events/conferences/urs_honors_poster_symposium/index.html

Start Date

3-26-2021 2:20 PM

End Date

3-26-2021 2:40 PM

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Mar 26th, 2:20 PM Mar 26th, 2:40 PM

The Effect of a Novel Hybrid Drug on the Inositol Signaling System in the Yeast Saccharomyces Cerevisiae

Bipolar Disorder is one of the major mental illnesses in the world. While there is insufficient understanding of the mechanism of the disease, many of the drugs used for treatment appear to work via the inositol signaling system. The purpose of this study is to develop a novel hybrid drug-containing valproate and caffeine and determine its impact on the inositol cell signaling system. To do so, the yeast Saccharomyces cerevisiae was grown in varying concentrations of the hybrid drug, and inositol concentration will be measured in cell extracts.

https://digitalcommons.andrews.edu/honors-undergraduate-poster-symposium/2021/symposium/13