P-31 Environmentally Friendly Heterogeneous General Synthesis of Ylidene Rhodanines
Abstract
Ylidene rhodanines have found broad applications in biomedical and material sciences, such as in pharmaceuticals and as sensors. A number of different methods have been reported in the scientific literature for their synthesis. Our ‘green chemistry’ approach involves use of a cheap, nontoxic, heterogeneous base promoter in refluxing ethanol. We have discovered that our calcium oxide promoted Knoevenagel condensation method is very simple, reliable, versatile and applicable to a wide structural diversity of ylidene rhodanines. This research was contributed to and performed by both high school and undergraduate students. It opens the door for easy access to and wider applications of this important class of organic compounds.
Location
Buller Hallway
Start Date
3-7-2014 2:30 PM
End Date
3-7-2014 4:00 PM
P-31 Environmentally Friendly Heterogeneous General Synthesis of Ylidene Rhodanines
Buller Hallway
Ylidene rhodanines have found broad applications in biomedical and material sciences, such as in pharmaceuticals and as sensors. A number of different methods have been reported in the scientific literature for their synthesis. Our ‘green chemistry’ approach involves use of a cheap, nontoxic, heterogeneous base promoter in refluxing ethanol. We have discovered that our calcium oxide promoted Knoevenagel condensation method is very simple, reliable, versatile and applicable to a wide structural diversity of ylidene rhodanines. This research was contributed to and performed by both high school and undergraduate students. It opens the door for easy access to and wider applications of this important class of organic compounds.
Acknowledgments
Undergraduate Research Scholar
Advisor: Desmond Murray, Chemistry & Biochemistry