Presentation Title
P-25 The association of the cumulative/lifetime duration of breast feeding and the development of post menopausal breast cancer. Results from Adventist Health study-2
Presenter Status
Research Coordinator, Department of Physical Therapy
Second Presenter Status
Department of Epidemiology, Biostatistics and Population Medicine, School of Public Health
Third Presenter Status
Department of Epidemiology, Biostatistics and Population Medicine, School of Public Health
Fourth Presenter Status
Department of Epidemiology, Biostatistics and Population Medicine, School of Public Health
Fifth Presenter Status
Department of Global Health, School of Public Health
Sixth Presenter Status
Department of Epidemiology, Biostatistics and Population Medicine, School of Public Health
Preferred Session
Poster Session
Start Date
30-10-2015 2:00 PM
End Date
30-10-2015 3:00 PM
Presentation Abstract
Methods: We also modeled the outcome variable breast cancer using attained age model in Cox proportional hazard regression analysis to assess the association. The models consisted of the main exposures; duration of breast feeding and initiation of breast feeding adjusted for age, education, live birth, age at menarche, age at first birth, period between first child birth and last child birth, body mass index, exercise, hormone replacement therapy (HRT), use of birth control pills, and family history of breast cancer.
Results: There was an inverse association between breast feeding and risk of breast cancer, 25% lower risk for those who have initiated breastfeeding, Months of breastfeeding was associated with risk of breast cancer, but the effect seems to be a threshold effect with any breastfeeding (1+ month) being protective compared to those who have not breastfed. Family history of breast cancer, recent HRT use, and higher education were associated with increased risk of breast cancer.
Conclusions: Breast feeding is associated with some reduction in risk of breast cancer, but the findings did not reach statistical significance. However the study is limited to a few cases hence wide confidence intervals. Further studies are required to investigate this relationship with a study sample with enough cases.
Key Words: Duration breastfeeding, women, post-menopausal, breast cancer
P-25 The association of the cumulative/lifetime duration of breast feeding and the development of post menopausal breast cancer. Results from Adventist Health study-2
Methods: We also modeled the outcome variable breast cancer using attained age model in Cox proportional hazard regression analysis to assess the association. The models consisted of the main exposures; duration of breast feeding and initiation of breast feeding adjusted for age, education, live birth, age at menarche, age at first birth, period between first child birth and last child birth, body mass index, exercise, hormone replacement therapy (HRT), use of birth control pills, and family history of breast cancer.
Results: There was an inverse association between breast feeding and risk of breast cancer, 25% lower risk for those who have initiated breastfeeding, Months of breastfeeding was associated with risk of breast cancer, but the effect seems to be a threshold effect with any breastfeeding (1+ month) being protective compared to those who have not breastfed. Family history of breast cancer, recent HRT use, and higher education were associated with increased risk of breast cancer.
Conclusions: Breast feeding is associated with some reduction in risk of breast cancer, but the findings did not reach statistical significance. However the study is limited to a few cases hence wide confidence intervals. Further studies are required to investigate this relationship with a study sample with enough cases.
Key Words: Duration breastfeeding, women, post-menopausal, breast cancer