P-33 Development of a novel biosensor setup of combined QCM-D and FET

Presenter Status

Department of Engineering and Computer Science

Second Presenter Status

Undergraduate Student, Department of Engineering and Computer Science

Third Presenter Status

Undergraduate Student, Department of Engineering and Computer Science

Location

Buller Hallway

Start Date

8-11-2012 3:00 PM

End Date

8-11-2012 5:00 PM

Presentation Abstract

A novel setup of a biosensor that combines an EGFET (extended gate field effect transistor) and a QCM-D (quartz crystal microbalance with dissipation) has been developed. The setup utilized a commercial, affordable MOSFET, hard wired to the QCM-D without having to undergo complicated nanofabrication procedures. This sensor was capable of detecting changes in electrochemical and thickness/flexibility during bio-molecular interactions. For the proof of concept, DNA fragments of H1N1 were detected in the setup. The sensor demonstrated in situ, label-free, and multi-modal characterization of bio-molecular interactions with high sensitivity and multiple parameters through a simple instrumentation.

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Nov 8th, 3:00 PM Nov 8th, 5:00 PM

P-33 Development of a novel biosensor setup of combined QCM-D and FET

Buller Hallway

A novel setup of a biosensor that combines an EGFET (extended gate field effect transistor) and a QCM-D (quartz crystal microbalance with dissipation) has been developed. The setup utilized a commercial, affordable MOSFET, hard wired to the QCM-D without having to undergo complicated nanofabrication procedures. This sensor was capable of detecting changes in electrochemical and thickness/flexibility during bio-molecular interactions. For the proof of concept, DNA fragments of H1N1 were detected in the setup. The sensor demonstrated in situ, label-free, and multi-modal characterization of bio-molecular interactions with high sensitivity and multiple parameters through a simple instrumentation.