Date of Award

2015

Document Type

Honors Thesis

Department

Chemistry & Biochemistry

First Advisor

Ryan T. Hayes

Abstract

The goal of this project was to investigate the use of NIR-spectroscopy to quantify the number of OH functional groups attached to poly(amido amine) or PAMAM dendrimers in a manner that is quick, cost effective and easily reproducible. Obtaining the approximate number of hydroxyl functional groups (OH#) in a dendrimer is crucial in determining what role it can play in bonding and reactivity to other molecules. NIR-spectroscopy has the potential to allow for the recovery of the sample or at least to minimize the amount needed for analysis while providing an accurate determination of the OH# of a dendrimer.

Subject Area

Near infrared spectroscopy., Dendrimers., Hydroxyl group.

Included in

Chemistry Commons

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