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"this paper analyzes the dynamics arising from interactions between typical elements of organizational culture such as leadership, strategic processes, and knowledge management. More specifically, it seeks to establish possible relationships between leadership based on spirituality and the processes of creating, sharing, and reusing knowledge. the goal of this analysis is to establish a link between spiritual leadership as a strategy of the study of spirituality in the workplace and knowledge management. the research is focused on the application of Louis Fry’s theory of spiritual leadership to a group of organizations made up of small and medium-sized enterprises (SMEs) located in Medellin, Colombia. Owing to the fact that the study’s interests are aimed at comprehending human actions in an organizational context, the ethnographic method, direct observation, and in-depth interviews were used as techniques for data collection. the most important findings of the research indicate that spiritual leadership fosters knowledge processes of the company being studied as it lays down an organizational culture that binds both beliefs and individual and corporate interests. this culture, based on spiritual values, promotes an organizational environment in which employees perceive that their spiritual needs are being satisfied and as a consequence, develop the required motivation to carry out actions and processes, including knowledge processes directed at the achievement of organizational goals. in addition, it was found in this particular case that the Adventist religion provides a set of beliefs which, when put into practice, strengthens leadership and the ability to influence others. Finally, it was noticed that even though there are potential benefits provided by spiritual leadership to the company’s knowledge management processes, its impact is limited because the company which was analyzed is unaware of the importance of these processes and the way to manage them."