Event Title

P-54 The Stabilization of Aqueous Ascorbic Acid Solutions Using PAMAM Dendrimers and Evaluation of Its Antioxidant Properties

Presenter Information

Chan Kim, Andrews UniversityFollow

Start Date

3-2-2018 2:30 PM

Description

Ascorbic acid is an essential enzymatic cofactor with antioxidant properties that is added to many beverages. However, due to its instability in aqueous solutions, ascorbic acid degrades readily when exposed to air and light. PAMAM (polyamidoamine) dendrimers were found to stabilize dilute concentrations of ascorbic acid solution. UV-Vis absorbance spectroscopy was used to monitor ascorbic acid degradation in the absence and presence of G2-PAMAM dendrimers while exposed to various types of light and levels of oxygen. The DPPH assay was then used to evaluate the ascorbic acid’s antioxidant efficacy while stabilized with PAMAM dendrimer solutions.

Acknowledgments

Ryan Hayes, PhD.

AU Office of Research & Creative Scholarship.

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Mar 2nd, 2:30 PM

P-54 The Stabilization of Aqueous Ascorbic Acid Solutions Using PAMAM Dendrimers and Evaluation of Its Antioxidant Properties

Ascorbic acid is an essential enzymatic cofactor with antioxidant properties that is added to many beverages. However, due to its instability in aqueous solutions, ascorbic acid degrades readily when exposed to air and light. PAMAM (polyamidoamine) dendrimers were found to stabilize dilute concentrations of ascorbic acid solution. UV-Vis absorbance spectroscopy was used to monitor ascorbic acid degradation in the absence and presence of G2-PAMAM dendrimers while exposed to various types of light and levels of oxygen. The DPPH assay was then used to evaluate the ascorbic acid’s antioxidant efficacy while stabilized with PAMAM dendrimer solutions.