Event Title

Synthesis of Imino Azachalcones as Potential Fluorescent Sensors for Metal Ions

Location

Buller Hall

Start Date

3-3-2017 2:30 PM

End Date

3-3-2017 4:00 PM

Description

The purpose of this project is to create imino azachalcones a potential new class of fluorescent and/or colorimetric sensors for metal ions. Our approach involves a two-step process: preparing imines from 2-acetylpyridine followed by reaction with aromatic aldehydes to synthesize imino azachalcones. These compounds have a bidentate recognition site and a conjugated ‘response’ subunit that we anticipate would function cooperatively as sensor molecules. This report focuses on the first step involving the optimization of reaction conditions for synthesis of 2-acetylpyridine imines. This involved reacting 2-acetylpyridine with a primary amine under a variety of reaction conditions. Acid strength, solvent polarity, and amine structure were varied in our search for optimal reaction conditions.

Acknowledgments

Dr. Desmond H. Murray

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Mar 3rd, 2:30 PM Mar 3rd, 4:00 PM

Synthesis of Imino Azachalcones as Potential Fluorescent Sensors for Metal Ions

Buller Hall

The purpose of this project is to create imino azachalcones a potential new class of fluorescent and/or colorimetric sensors for metal ions. Our approach involves a two-step process: preparing imines from 2-acetylpyridine followed by reaction with aromatic aldehydes to synthesize imino azachalcones. These compounds have a bidentate recognition site and a conjugated ‘response’ subunit that we anticipate would function cooperatively as sensor molecules. This report focuses on the first step involving the optimization of reaction conditions for synthesis of 2-acetylpyridine imines. This involved reacting 2-acetylpyridine with a primary amine under a variety of reaction conditions. Acid strength, solvent polarity, and amine structure were varied in our search for optimal reaction conditions.