Event Title

Fluorescence Analysis of PAMAM Dendrimers

Presenter Information

Ansel Nam, Andrews University

Start Date

3-3-2017 2:30 PM

End Date

3-3-2017 4:00 PM

Description

Despite their lack of conjugation, polyamidoamine (PAMAM) dendrimers are intrinsically fluorescent, and this fluorescent has been previously reported to increase by lowering the solvent’s pH. The mechanism of fluorescence from these polymeric, non-conjugated, nanostructures is poorly understood so the goal of this research is to study the role of solvent pH, dendrimer concentration, and dendrimer size on this property. The fluorescent emission efficiency (quantum yield) was also studied and compared to another highly fluorescent molecule, fluorescein. These results will help improve our understanding of dendrimer fluorescence and how it can be used for analysis in biological or chemical systems.

Acknowledgments

Dr. Ryan Hayes

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Mar 3rd, 2:30 PM Mar 3rd, 4:00 PM

Fluorescence Analysis of PAMAM Dendrimers

Despite their lack of conjugation, polyamidoamine (PAMAM) dendrimers are intrinsically fluorescent, and this fluorescent has been previously reported to increase by lowering the solvent’s pH. The mechanism of fluorescence from these polymeric, non-conjugated, nanostructures is poorly understood so the goal of this research is to study the role of solvent pH, dendrimer concentration, and dendrimer size on this property. The fluorescent emission efficiency (quantum yield) was also studied and compared to another highly fluorescent molecule, fluorescein. These results will help improve our understanding of dendrimer fluorescence and how it can be used for analysis in biological or chemical systems.