Event Title

The Potential of Omega-3 Fatty Acids in Treating Bipolar Disorder through the Metabolic Pathway of Inositol

Location

Buller Hall

Start Date

2-26-2016 2:30 PM

End Date

2-26-2016 4:00 PM

Description

Bipolar disorder is a mental disorder characterized by extreme mood swings. Omega-3-fatty acids have been shown to relieve symptoms of bipolar disorder and are not associated with the negative side effects of lithium and valproate, the two most common treatments of the disorder. However, omega-3-fatty acids’ mechanism of action remains unknown. This study examined the effects of omega-3 fatty acid docosahexaenoic acid (DHA) on intracellular inositol levels of Saccharomyces Cerevisiae. We show that similar to valproate, DHA decreases the growth of Saccharomyces Cerevisiae. We also show that unlike valproate, DHA does not decrease intracellular inositol levels.

Acknowledgments

Dr. Marlene Murray

This document is currently not available here.

Share

COinS
 
Feb 26th, 2:30 PM Feb 26th, 4:00 PM

The Potential of Omega-3 Fatty Acids in Treating Bipolar Disorder through the Metabolic Pathway of Inositol

Buller Hall

Bipolar disorder is a mental disorder characterized by extreme mood swings. Omega-3-fatty acids have been shown to relieve symptoms of bipolar disorder and are not associated with the negative side effects of lithium and valproate, the two most common treatments of the disorder. However, omega-3-fatty acids’ mechanism of action remains unknown. This study examined the effects of omega-3 fatty acid docosahexaenoic acid (DHA) on intracellular inositol levels of Saccharomyces Cerevisiae. We show that similar to valproate, DHA decreases the growth of Saccharomyces Cerevisiae. We also show that unlike valproate, DHA does not decrease intracellular inositol levels.