Presentation Title

P-35 Paper Analytical Devices Method and SERS Method in Detecting Some Illicit Drugs

Presenter Status

Professor, Chemistry

Preferred Session

Poster Session

Start Date

26-10-2018 2:00 PM

End Date

26-10-2018 3:00 PM

Presentation Abstract

Paper test cards coupled with surface-enhanced Raman spectroscopy (SERS) gives a simple method to identify common illicit drugs. We have successfully detected samples of cocaine hydrochloride, crack cocaine, heroin, and methamphetamine, and can discriminate between these drugs and a variety of distractor substances and legal medications. The initial step involves running multiple color tests in parallel using a paper analytical device (PAD). However, the PADs have limitations of quantifying these drugs. Therefore, for authentication and quantification of these drugs we are incorporating a surface-enhanced Raman scattering (SERS) functionality on the paper cards. SERS spectra utilizing both citrate stabilized as well as naked metal colloids would be monitored by aggregating silver or gold nanoparticles with 0. 1 – 1.0 mM cocaine hydrochloride or methamphetamine.

Getahun Merga, 1,2 Tammy Leong, 2 Noah Chan,2 Michael Trujillo, 1 Tracy Cleary,1 Jon P. Camden,1 and Marya Lieberman1

1 Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556

2 Department of Chemistry and Biochemistry, Andrews University, Berrien Springs, Michigan, 49104

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Oct 26th, 2:00 PM Oct 26th, 3:00 PM

P-35 Paper Analytical Devices Method and SERS Method in Detecting Some Illicit Drugs

Paper test cards coupled with surface-enhanced Raman spectroscopy (SERS) gives a simple method to identify common illicit drugs. We have successfully detected samples of cocaine hydrochloride, crack cocaine, heroin, and methamphetamine, and can discriminate between these drugs and a variety of distractor substances and legal medications. The initial step involves running multiple color tests in parallel using a paper analytical device (PAD). However, the PADs have limitations of quantifying these drugs. Therefore, for authentication and quantification of these drugs we are incorporating a surface-enhanced Raman scattering (SERS) functionality on the paper cards. SERS spectra utilizing both citrate stabilized as well as naked metal colloids would be monitored by aggregating silver or gold nanoparticles with 0. 1 – 1.0 mM cocaine hydrochloride or methamphetamine.

Getahun Merga, 1,2 Tammy Leong, 2 Noah Chan,2 Michael Trujillo, 1 Tracy Cleary,1 Jon P. Camden,1 and Marya Lieberman1

1 Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556

2 Department of Chemistry and Biochemistry, Andrews University, Berrien Springs, Michigan, 49104