Presentation Title

Investigation of 1,3-Dipolar Cycloadditions: Synthesis of Isoxazoline and Thiolactam Heterocycles as anti- M. tuberculosis Compounds

Presenter Information

Lisa Ahlberg, Andrews University

Presenter Status

Faculty

Session

E-1

Location

CSH Room 108

Start Date

9-5-2014 11:00 AM

End Date

9-5-2014 11:30 AM

Presentation Abstract

Development of highly antibiotic resistant strains of infections such as staphylococcus and tuberculosis warrant the search for new antibacterial chemotherapies. With vanishing antibiotic therapies available for such infections and with little pharmaceutical company input into these developing world problems, it is critical for many researchers to investigate novel therapies against these bacterial threats. We are particularly interested in 1,3-Di-polar cycloaddition chemistry as an approach to heterocycles that may be pharmaceutically useful against such threats.

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May 9th, 11:00 AM May 9th, 11:30 AM

Investigation of 1,3-Dipolar Cycloadditions: Synthesis of Isoxazoline and Thiolactam Heterocycles as anti- M. tuberculosis Compounds

CSH Room 108

Development of highly antibiotic resistant strains of infections such as staphylococcus and tuberculosis warrant the search for new antibacterial chemotherapies. With vanishing antibiotic therapies available for such infections and with little pharmaceutical company input into these developing world problems, it is critical for many researchers to investigate novel therapies against these bacterial threats. We are particularly interested in 1,3-Di-polar cycloaddition chemistry as an approach to heterocycles that may be pharmaceutically useful against such threats.